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KMID : 0829220090330010047
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Korean Journal of Oral and Maxillofacial Pathology
2009 Volume.33 No. 1 p.47 ~ p.52
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Combined Zygomycosis and Aspergillosis of The Maxillary Sinus
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Cho Yeong-Ah
Yoon Hye-Jung
Hong Seong-Doo
Lee Jae-Il
Hong Sam-Pyo
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Abstract
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Zygomycosis and aspergillosis are representative filamentous fungal infections in the sinonasal region. However, their combined form seldom occurs. This report describes one case of zygomycosis and aspergillosis occurring in a patient that did not have diabetes or any other immunocompromising conditions. The patient presented with a history of intermittent swelling and pus discharge from the gingiva of the right maxillary posterior teeth. The radiographs demonstrated a periapical radiolucency around the right maxillary first molar, together with mild haziness and mucosal thickening of the right maxillary sinus. Under the clinical impression of odontogenic sinusitis, a Caldwell-Luc operation was performed. However, the final diagnosis based on microscopic examination was combined zygomycosis and aspergillosis. Previous studies of zygomycosis occurring alone describe a very aggressive clinical course, including necrosis of tissue,cranial nerve involvement and death. Our patient did not show any of these symptoms, and recovered after surgical debridement only. It can be concluded from the present case that the prognosis of fungal infections depends on the immune status of the host, rather than behavior of the fungi.
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KEYWORD
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Zygomycosis, Aspergillosis, Fungal sinusitis, Fungus ball
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